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Guideline for the Assessment and Management of Crush Syndrome

Updated: Dec 15, 2025

References

[1] Joubert IM. Rhabdomyolysis, Crush Injury & Crush Syndrome. In: Jacks R, editor. The Trauma Manual, 2nd Ed. University of the Witwatersrand, Johannesburg. 2021; p.73-5.

[2] Bosch X, Poch E, Grau JM. Rhabdomyolysis and acute kidney injury. N Engl J Med. 2009;36(1):62-72.

[3] Jaber S, Paugam C, Futier E, et al. Sodium bicarbonate therapy for patients with severe metabolic acidaemia in the intensive care unit (BICAR-ICU): a multicentre, open-label, randomised controlled, phase 3 trial. Lancet. 2018;392(10141):31-40.

[4] Jung B, Jabaudon M, De Jong A, et al. Sodium bicarbonate for severe metabolic acidemia and acute kidney injury: the BICARICU-2 randomized clinical trial. JAMA. 2025;334(22):2000-10.

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